Pendulum GLP-1 Probiotic
by Pendulum Therapeutics · capsule ·
Strong science pedigree on Akkermansia, but a proprietary CFU blend and refrigeration requirement.
- Format
- capsule Pill
- Best price
- $2.63 per serving
- Pathways
- 3 hunger dimensions
- Headline dose
- Proprietary Akkermansia muciniphila
- Caffeine
- Caffeine-free evening-friendly
- Bloat risk
- Low Probiotic, trace fiber
3/7 hunger pathways
- GLP-1 / gut-hormone Akkermansia muciniphila, Clostridium butyricum
- Gut microbiome / prebiotic Bifidobacterium infantis, Probiotic blend, Chicory inulin
- Blood-sugar stability
How it scores
Every score is derived from publicly verifiable facts. See the full methodology and Value Index formula.
Ingredients & doses
| Ingredient | Dose | Pathway | Notes |
|---|---|---|---|
| Akkermansia muciniphila (WB-STR-0001) | Undisclosed proprietary blend | GLP-1 / gut-hormone | Generates postbiotics linked to GLP-1 signaling; strain dose hidden in the blend. |
| Clostridium butyricum (WB-STR-0006) | Undisclosed proprietary blend | GLP-1 / gut-hormone | Produces butyrate; strain dose hidden. |
| Bifidobacterium infantis (WB-STR-0002) | Undisclosed proprietary blend | Gut microbiome / prebiotic | |
| Probiotic blend (total) | 500 million AFU proprietary blend | Gut microbiome / prebiotic | Total across three strains; per-strain breakdown not disclosed. |
| Chicory inulin | 174 mg | Gut microbiome / prebiotic | Prebiotic fiber to support the strains. |
How it claims to work
Probiotic strains described as producing short-chain-fatty-acid postbiotics (butyrate, propionate, acetate) and the metabolite p9 in the gut, which the brand says supports the body’s own GLP-1 signaling and satiety.
The evidence
Akkermansia muciniphila has human and preclinical research linking it to metabolic and GLP-1 pathways, but there is no published RCT showing this consumer formula causes weight loss or measurable GLP-1 increases.
Strengths
- Akkermansia has the strongest individual research pedigree of the probiotic actives.
- Caffeine-free, single small capsule.
- Disclosed prebiotic inulin to feed the strains.
Watch-outs
- Per-strain doses are hidden inside a proprietary blend.
- Needs refrigeration to preserve potency — a routine and travel hassle.
- No RCT on the finished product for weight or GLP-1 outcomes.
Price & value
Taste & format: One small acid-resistant capsule once daily with food; flavorless, but recommended to be refrigerated to preserve the live strains.